What is a clean room

Clean rooms, also known as cleanrooms, are usually used as part of professional industrial production or scientific research, including the manufacturing of pharmaceuticals, integrated circuits, CRTs, LCDs, OLEDs and microled displays. Clean rooms are designed to maintain extremely low levels of particles, such as dust, airborne organisms, or vaporized particles. Specifically, the clean room has a controlled pollution level, which is specified by the number of particles per cubic meter at the specified particle size. A clean room may also refer to any given accommodation space in which particulate pollution is reduced and other environmental parameters such as temperature, humidity and pressure are controlled.

In the pharmaceutical sense, a clean room refers to a room that meets the requirements of GMP as defined in the GMP sterility specification (i.e. Annex 1 of EU and pic/s GMP guidelines and other standards and guidelines required by local health authorities). It is a combination of engineering design, manufacturing, completion and operation control (control strategy) required to convert an ordinary room into a clean room.

Clean rooms are used in many industries. Clean rooms can be found wherever small particles will adversely affect the production process. They vary in size and complexity, and are widely used in semiconductor manufacturing, pharmaceutical, biotechnology, medical equipment, life sciences and other industries, as well as key process manufacturing common in the Ministry of aerospace, optics, military and energy.